Isotopically Labeled Compounds
Medchemexpress LLC Nonanoic acid-d4 (Pelargonic acid-d4) | 1219795-27-3 | 10 MG
Nonanoic acid-d4 is the deuterium labeled Nonanoic acid, a naturally-occurring saturated fatty acid with nine carbon atoms. It significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Reduces bacterial translocation
- Enhances antibacterial activity
- Increases secretion of porcine β-defensins 1 (pBD-1) and pBD-2
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development
Medchemexpress LLC Vildagliptin-d3 | 1217546-82-1 | C17H22D3N3O2 | 500 UG
Vildagliptin-d3 is a deuterium labeled Vildagliptin. It is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. It possesses excellent oral bioavailability and potent antihyperglycemic activity. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Sodium propionate-d3 | 1210410-35-7 | MFCD04975446 | 98.4% | 99.08 | C3H2D3NaO2 | 10 MG
Sodium Propionate-d3 is a deuterium-labeled form of sodium propionate intended for research use. It serves as an isotopically labeled standard or tracer in analytical, metabolic, and biochemical studies.
- Isotopically labeled standard for mass spectrometry and tracer studies.
- Molecular formula C3H2D3NaO2 and molecular weight 99.08.
- CAS number 1210410-35-7 for unique substance identification.
- Purity approximately 98.4% suitable for analytical applications.
- Supplied as a 10 MG solid for small-scale experiments.
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | 98.8% | 5 MG
Nizatidine-d3 is the deuterium-labeled form of Nizatidine, a potent and orally active histamine H2 receptor antagonist. It is used in the research of stomach and intestinal ulcers by decreasing gastric acid secretion and preventing ulcer recurrence. Its deuterium labeling makes it valuable as a tracer and internal standard for quantitative analysis in drug development.
- Deuterium labeled Nizatidine
- Potent and orally active histamine H2 receptor antagonist
- Used for research of stomach and intestines ulcers
- Decreases secretion of gastric acid
- Prevents ulcers from returning after healing in animal models
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Clozapine-d4 | 204395-52-8 | 99.5% | C18H15D4ClN4 | 1 MG
Clozapine-d4 is a deuterium-labeled form of Clozapine, an antipsychotic used in schizophrenia research. It exhibits high affinity for various neuroreceptors. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Sudan III-d6 | 1014689-17-8 | 93.0% | 5 MG
Sudan III-d6 is a deuterium-labeled Sudan III. Sudan III is a hydrophobic bisazo dye. It is intended for research use only and not for sale to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements incorporated into drug molecules can be used as tracers for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Ketotifen-d3 fumarate | 1795138-23-6 | 99.2% | 50 MG
Ketotifen-d3 (fumarate) is a deuterium-labeled version of Ketotifen fumarate. This compound is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, utilized for the prevention of asthma attacks.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
![Medchemexpress LLC 3H-imidazo[4,5-f]quinoxalin-2-amine, 8-methyl-3-(methyl-d3) | 122457-31-2 | MFCD00210329 | 99.0% | 216.26 g/mol | C11H8D3N5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285110.png-250.jpg)
Medchemexpress LLC 3H-imidazo[4,5-f]quinoxalin-2-amine, 8-methyl-3-(methyl-d3) | 122457-31-2 | MFCD00210329 | 99.0% | 216.26 g/mol | C11H8D3N5 | 5 MG
MeIQx-d3 is the triply deuterated isotopologue of MeIQx supplied as a high-purity analytical standard for use as an internal standard and tracer in mass spectrometry and quantitative exposure studies.
- Triply deuterated isotopologue for use as an internal standard.
- High purity: 99.0%.
- Molecular formula C11H8D3N5; molecular weight 216.26 g/mol.
- Available as a 5 MG powder package.
- Storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Applications include LC-MS/MS quantitation, tracer studies, and method development.
Medchemexpress LLC Nemonoxacin-d3 | 99.9% | 374.45 | 1 MG
Nemonoxacin-d3 is a deuterated compound, chemically known as 3-Quinolinecarboxylic acid, 7-[(3S,5S)-3-amino-5-methyl-1-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-d3. This compound has a molecular weight of 374.45 and is supplied as a high-purity material, primarily intended for research applications.
- High purity of 99.9%
- Confirmed structure by 1H NMR and LCMS
- Isotopic enrichment of 99.76%
- Off-white to light yellow solid appearance
- Stable for extended periods when stored properly
Medchemexpress LLC Cefepime-d3 (sulfate) | 107648-78-2 | 99.5% | 581.66 g/mol | C19H23D3N6O9S3 | 1 MG
Cefepime-d3 (sulfate) is a deuterium-labeled analogue of the antibiotic cefepime provided as a small, pre-weighed sulfate salt for analytical and research applications. It is intended for use as an internal standard or tracer in mass spectrometry workflows and method development; not for human or veterinary use.
- Deuterium-labeled internal standard suitable for LC-MS/MS quantitation.
- High purity (99.5%) for reliable analytical performance.
- Supplied in small pre-weighed vials (e.g., 1 mg) for method development.
- Sulfate salt form that matches analyte chemistry.
- Suitable for pharmacokinetic, bioanalysis, and tracer studies.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC Cimetidine-d3 | 1185237-29-9 | C10H13D3N6S | 1 MG
Cimetidine-d3 is the deuterium-labeled form of Cimetidine. Cimetidine (SKF-92334) is an orally active, inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. It functions as an inverse agonist and has demonstrated anti-cancer and anti-inflammatory activities.
- It can be used as a tracer.
- It can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Olmesartan-d4 (RNH-6270-d4) | 1420880-41-6 | MFCD10567132 | 98.8% | 450.53 | C24H22D4N6O3 | 10 MG
Olmesartan-d4 is a deuterium-labeled analogue of olmesartan supplied as a 10 mg research-grade standard for laboratory analytical use. It is intended as a tracer or internal standard for quantitative methods and is not for human or veterinary use.
- Deuterium-labeled internal standard for quantitative analysis.
- High purity: 98.83% suitable for analytical assays.
- Molecular weight 450.53; formula C24H22D4N6O3.
- Soluble in DMSO (20.83 mg/mL); may require ultrasonic treatment.
- Recommended storage: powder -20 °C; in solvent -80 °C (6 months) or -20 °C (1 month).
- Supplied as a 10 mg quantity for analytical workflows.